Uncertainty

I must admit at first I was a bit surprised to learn that light particles can appear differently depending on how they are observed and measured. This concept was clear to me in terms of human relations, because of our psychological make up and conditioning which influences our perception of each other and can change according to experience. I guess the distinction I had been making was that something like light particles don't have a psyche and therefore should remain constant every time they are observed. Of course I was not considering the role that the observer and the condition of the observation play in this. The reason I think that a shoe is an object to put on my feet is because that is how I have been taught to use it, but how would someone who has never seen a shoe perceive it? They might see it as something to eat their food out of, or some kind of center piece for the dining room table. If there is no mind perceiving, then what is the nature of anything really? I have heard in Buddhist philosophy that nothing is inherently existent and I can see how Uncertainty fits into this notion. It seems to make sense that if there is an observer creating a particular situation, then that is what brings their observation into existence, but it is processed through their personal filter and therefore does not necessarily capture the complete nature of what is being observed.